If you hold a Mississippi Advanced Practice Registered Nurse (APRN) credential, you maintain your status primarily through national certification, with APRN licenses renewing biennially in even-numbered years. Mississippi adds a distinctive requirement: every APRN must complete 5 contact hours of CE in controlled substances/scheduled medications each cycle — regardless of whether you hold a DEA registration. Below is the full breakdown.
5 controlled-substance hours
Required of all APRNs every cycle, even without DEA registration.
National certification
Maintained as the basis of the APRN credential.
Renews even years
APRN licenses renew biennially in even-numbered years.
CE Broker
APRNs are encouraged to track CE through CE Broker.
How Mississippi nurse practitioners renew
Mississippi APRNs maintain their credential through national certification, with APRN licenses renewing biennially in even-numbered years.
Controlled-substance requirement
- Controlled substances: 5 contact hours each cycle in controlled substances/scheduled medications, required of all APRNs regardless of DEA registration.
Renewal cycle and deadlines
Mississippi APRN licenses renew biennially in even-numbered years. Complete and document your 5 controlled-substance hours, and keep national certification current, before your renewal deadline.
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View pricingMississippi Nurse Practitioners (NP/APRN) CME at a glance
- Controlled Substances / Scheduled Medications5 hrs
Every APRN must complete 5 contact hours of CE in controlled substances/scheduled medications each cycle, regardless of DEA registration status.
Always confirm with your licensing board
Mississippi APRNs (NP, CRNA, CNM) maintain their credential primarily through national certification, and APRN licenses renew biennially in even-numbered years. Mississippi specifically requires every APRN to complete 5 contact hours of CE in controlled substances/scheduled medications each cycle, regardless of whether the APRN holds a DEA registration. APRNs with a lapsed license must complete 40 CE hours for reinstatement.
CE requirements change. Confirm current rules with the Mississippi Board of Nursing before relying on these figures.
Source: Mississippi Board of Nursing. Board website · Researched as of 2026-06-01 · CME rules change; this is administrative guidance, not legal or CME-accreditation advice.
Licensed in more than one state?
APRN Compact: enacted but not yet active. Enacted by several states but NOT yet operational — no multistate APRN license is being issued. APRNs/NPs license state-by-state today (an APRN who is also an RN may hold an NLC multistate RN license).
Each state license carries its own CME requirement and renewal date — if you hold more than one, you need a plan for each.
Also licensing in Mississippi or beyond?
Our sister teams handle the licensing side with the same concierge service.
White Glove APRN
Advanced practice (NP, CRNA, CNS, CNM) state-by-state licensing, DEA, and CSR. The APRN Compact is not yet active, so we handle single-state licensing.
whitegloveaprn.comWhite Glove NLC
RN and LPN/LVN licensing — Nurse Licensure Compact (NLC) multistate and single-state.
whiteglovenlc.comMississippi Nurse Practitioner CE Requirements — Frequently Asked Questions
How many CE hours do Mississippi nurse practitioners need?
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At minimum, 5 controlled-substance CE hours each cycle, plus maintaining national certification.
Do Mississippi APRNs need controlled-substance CE without a DEA number?
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Yes — all APRNs must complete 5 controlled-substance hours each cycle regardless of DEA registration.
When do Mississippi APRN licenses renew?
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Biennially in even-numbered years.
Related
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